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Dr. Upendra Sharma

Senior Scientist

  • Specialisation:Catalysis; C-H Activation; Natural Product Chemistry; Analytical Chemistry
  • Email: upendra@ihbt.res.in
  • Qualification: Ph.D.
  • Phone: 01894 230426
Group Website: C-H Activation & Phytochemistry
Organic Synthesis & Catalysis
  • C-H Activation/functionalization
  • Heterocycles Synthesis

Phytochemistry : (Himalayan Medicinal Plants)

Isolation and structure elucidation of plant secondary metabolites

Standardization of plant extracts (targetted activity & four marker compounds)

Development of analytical methods (UPLC, GC, and NMR)

Chemical profiling using NMR (1D & 2D), UPLC-MS/MS, and GC-MS/MS


Medicinal Chemistry

Discovery of new heterocycles as potential therapeutic agents

Scientific validation of plant traditional knowledge (Ayush or Phytopharma route)

Selected Publications in the last three years
Organic Synthesis and Catalysis

134. Advanced Synthesis & Catalysis, 2022, 364, 897. [Link]

133. Asian Journal of Organic Chemistry, 2022, doi.org/10.1002/ajoc.202100804 [Link]

132. The Chemical Records, 2022, 22, e202100271. [Link]

131. Chemical Communications, 2021, 57, 11613. [Link] Highlighted on Front Cover [Link]

130. Organic & Biomolecular Chemistry, 2021, 19, 9675.[Link]

129. The Journal of Organic Chemistry, 2021, 86, 13754. [Link]

128. European Journal of Organic Chemistry, 2021, 2021, 5443. [Link]

128. European Journal of Organic Chemistry, 2021, 2021, 5443. [Link]

127. React. Chem. Eng., 2021, 6, 2087[Link] [Invited for Emerging Investigators Series]

126. The Journal of Organic Chemistry 2021, 86, 6612. [Link]

125. The Journal of Organic Chemistry, 2021, 86, 6449. [Link]

124. Organic & Biomolecular Chemistry, 2021, 19, 4014. [Link]

123. Catalysis Reviews, 2020, doi.org/10.1080/01614940.2020.183.9849. [Link]

122. ACS Sustainable Chemistry & Engineering, 2020, 8, 12902. [Link]

121. Chemistry-A European Journal, 2020, 26, 4396 [Hot Paper].[Link]

120. Organic Letters, 2020, 22, 305.[Link]

119. The Journal of Organic Chemistry, 2020, 85, 11844 [Most Read Article]. [Link]

118. The Journal of Organic Chemistry, 2020, 85, 9244. [Link]

117. The Journal of Organic Chemistry, 2020, 85, 1181.[Link]


Phytochemistry

116. Sepration and Purification Technology, 2022, accepted.

115. BMC Complementary Medicine and Therpies, 2022, accepted.

114. Journal of Ethanopharmacology, 2022, 287, 114931. [Link]

113. Molecules, 2022, 27, 633.

112. Natural Product Research, 2022, 36, 37.[Link]

111. J. Biomol. Struct. Dyn., 2021, doi.org/10.1080/07391102.2021.2003864.[Link]

110. Scientific Reports, 2021, 20095.[Link]

109. Journal of Ethnopharmacology, 2021, 274, 113850. [Link]

108. Analytical Science Advance, 2021, 2, 579-593. [Link]

107. Journal of Pharmacy and Pharmacology, 2021, 73, 487. [Link]

106. Pest Management Science, 2021, 77, 956. [Link]

105. Journal of Molecular Graphics and Modelling, 2021, 106, 107916.

104. Journal of Ethnopharmacology, 2020, 262, 113185. [Link]

103. Phytochemical Analysis, 2020, 31, 861. [Link]

102. Natural Product Research, 2020, 34, 233. [Link]

101. Natural Product Research, 2020, 34, 2051. [Link]

Complete List of Publications

Member of Early Career Board of Science of Synthesis (2022-).

One Year Advance Promotion i.e. Merit Promotion from Scientist to Senior Scientist.

Member of Early Career Advisory Board of Asian Journal of Organic Chemistry. Link

Manjushree Pal Memorial Award for Best Oral Presentation from Ethanopharmacology Society of India, Kolkata (2017)

Thieme Chemistry Journal Award (2016)

Postdoc Fellowship KAIST, South Korea (2014)

D S Kothari Postdoc Fellowship (2012)

Fast Track Young Scientist project for three years (2012)

CSIR Senior Research Fellowship (2009)

CSIR-Junior Research Fellowship (2007)

GATE (2007)

CSIR-NET (2006)

Book Chapters

8. Integrated Approach for the Quality Assurance of Commercially Important Himalayan Medicinal Plants.

P. S. Bora, P. S. Suresh, S. Kumari, Anmol, S. Puri, and U. Sharma.*

Ekiert H. M., Ramawat K. G., Arora J. (eds)

Medcinal Plants. Sustainable Development and Biodiversity (Springer), 28, 721-768. Link

7. Steroidal Sapogenins from Genus Trillium: Chemistry, Synthesis, and Opportunities in Neuro-active Steroids Designing.

P. S. Suresh, V. Bhatt, P. P. Singh, and U. Sharma.*

Studies in Natural Product Chemistry (Elsevier), 2021, 68, 67-95. Link

6. Direct Arylation via C-H activation.

U. Sharma, A. Modak, S. Maity, A. Maji, and D. Maiti.

Thomas CoIacot eds., Introduction to New Trends in Cross-Coupling: Theory and Applications (RSC) 2014. Link

Complete List of Book Chapters

3. An Eco-friendly Process for Isolation of Fiber from Plant Species and Product thereof. M. Sharma, S. Thakur, U. Sharma, and S. Kumar. Ref. No. 202011034404. Date of Filing: 11-08-2020.

2. Palladium-Catalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins. D. Maiti, U. Sharma, and N. Tagoti. Indian Patent No. 299110; Date of Grant: 24-07-2018.

1. Benzothiazole Substituted Phthalimide Analogues as Potential Angiogenesis Inhibitors.
B. Singh, S. Chattergi, N. Kumar and U. Sharma.
Indian Patent No. 318680; Date of Grant: 22-08-2019.

Ph.D. Fellows
  • Mr. Devesh Chandra
  • Ms. Diksha Parmar
  • Ms. Surekha Kumari
  • Mr. Sumit
  • Ms. Manisha
  • Mr. Anmol
  • Mr. Rohit Kumar
  • Mr. Shiv Shankar Gupta
  • Mr. Prithvi Pal Singh
Group Alumni (Ph.D. Thesis Awarded)
  • Dr. Patil Shivprasad Suresh, Feb. 2022.
  • Dr. Ankit Kumar Dhiman, December 2021.
  • Dr. Inder Kumar, July 2021, Current Position: Asst. Prof. at Govt. Degree College (HPU)
  • Dr. Rakesh Kumar, Feb. 2020; Current Position: Postdoc Fellow Link
  • Dr. Ritika Sharma, July 2019
  • Dr. Deepali Katoch, July 2019
  • Dr. Vinod Bhatt, Feb. 2018
Project Fellows
  • Ms. Divya Rana, PA-II, Feb. 2018-June 2019.
  • Ms. Shivani Puri, PA-II, Sept. 2018-March 2020.
  • Ms. Kavita Devi, PA-II, July 2019-March 2020.
Postdocs
  • Dr. Vinod Bhatt, Postdoc, 2018-2019.
  • Dr. Ashun Chaudhary, Postdoc, 2016-2018; Current Position: Asst. Prof. at CUHP.
  • Dr. Rakesh Kumar, Postdoc, 2016-2017; Current Position: Asst. Prof. at NIT Jalandhar.
Prospective Team Members

Two Ph.D. Positions Available in the Area of C-H Activation for JRF Candidates. Postdoc Positions are Available for Self-Motivated Persons.